Systems Immunology | Systems Biology | Systems Medicine
News
We seek to construct predictive models describing the dynamical behavior of the immune system via systems biological approaches. Using these models, we wish to better understand complex and nonlinear immune behavior in its entirety. Ultimately, we design therapies to predictably modulate such behavior to the direction we desire to help cure infectious, malignant, and autoimmune diseases occurring due to dysregulations of the immune system. To realize this, we need to incorporate sufficient biological realities of the immune system into the models in two aspects: 1) the multiscale nature spanning across genes, cells, tissues, organs, and organisms/populations and 2) the high-throughput nature consisting of numerous molecular and cellular players with intricate interactions among each other. Therefore, we will develop computational frameworks to encompass data from various sources – multi-omics, clinics, or images using methods from machine learning, Bayesian statistics, and data science within traditional mathematical modeling to be deployable to individualized therapies of immune diseases in the era of ‘precision’ medicine.
Curriculum Vitae
-2022-: Assistant Professor, Biomedical Engineering Department, UNIST
-2022-2022: Senior researcher, Korea Virus Research Institute, Institute for Basic Science
-2020-2022: Fellow, Department of Pharmacology, Yonsei University College of Medicine
-2015-2020: Predoctoral Visiting Fellow, Laboratory of Immune System Biology, NIAID, NIH
Academic Credential
-2020: Ph.D., Biophysics, University of Maryland, College Park
-2014: M.D., Yonsei University
-2008: B.S., Physics, Seoul National University
Awards/Honors/Memberships
Awards
-Woongbi Next Generation Research Award, Korean Association of Immunologist International Meeting 2021
Membership
-American Physical Society
-The Korean Association of Immunologist
-Korean Society for Clinical Pharmacology & Therapeutics