Because intracellular or intercellular signaling controls various physiological activities in the living organisms, the malfunction of these signaling systems is directly linked with cancer and other diseases. There are many attempts to identify molecular diagnostic and therapeutic targets by tracking abnormalities in these signal pathways inside cancer cells. However, studies of the cell-cell communication between cancer cells and surrounding healthy cells have not been studied sufficiently. The C5 center aims to present a new strategy to fight against cancer by understanding intercellular signaling communication that involves controlling the growth of cancer cells and metastasis.