We studies the function of human genes involved in diseases, based on their deep homology in multiple organisms. By utilizing large-scale functional genomic data in multiple organisms, we computationally infer the role of uncharacterized genes (or novel function of already characterized genes) in phenotype that we are interested in. By integrating engineering perspectives, we also develop novel experimental platform to validate our predictions in model organisms.
Curriculum Vitae-
- -2025.09~Current: Professor, Department of Biomedical Engineering, UNIST
- -2021-2025.08: Associate Professor, Department of Biomedical Engineering, UNIST
- -2015-2020: Assistant Professor, UNIST
- -2012-2015: Research Fellow, Center for Systems and Synthetic Biology, University of Texas at Austin, USA
- -2001-2005: Researcher, Biochip Project, Samsung Adv. Inst. of Tech(SAIT) / Samsung Electronics, Korea
Academic Credential
- –2012: Ph.D. in Cell & Molecular Biology, University of Texas at Austin, USA
- -2006: M.Phil. in Computational Biology, University of Cambridge/Clare Hall, UK
- -2000: M.S. in Chemical Engineering, Seoul National University, Korea
- -1998: B.S. in Chemical Engineering, Seoul National University, Korea
Publications
- –Proc Natl Acad Sci USA Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas 9, Kwon T, Ra JS, Lee S, Baek I-J, Khim KW, Lee EA, Song EK, Otarbayev D, Jung W, Park YH, Wie M, Bae J, Cheng H, Park JH, Kim N, Seo Y, Yun S, Kim HE, Moon HE, Paek SH, Park TJ, Park YU, Rhee H, Choi JH, Cho SW, Myung K (2022)
- –Aging Cell, Adaptive cellular response of the substantia nigra dopaminergic neurons upon age-dependent iron accumulation Kwon K, Cho H, Lee S, Cho EJ, Yu W, Kok CYL, Je HS, Kim JI, Cho HJ, Kwon T (2022)
- –Cell Rep, Regulation of RNA localization during oocyte maturation by dynamic RNA ER association and remodeling of the ER, Hwang H, Yun S, Arcanjo RB, Divyanshi Chen S, Mei W, Nowak RA, Kwon T, Yang J (2022)
