Mutations in protein coding-sequence and regulatory elements can cause altered gene expression which can cause diseases. Mis-regulated gene expression can be corrected by direct editing of genomic elements. Indeed, artificial transcription factors can regulate gene expression resulting rescue phenotypes. The fact that less than 2% of our genome encodes protein suggests regulatory elements are promising candidates for therapeutics. We aim to identify and develop strategy for correction of disease-associated aberrations using CRISPR and its derivative technology.
이력
- – 2022.09~Present: Associate Professor, UNIST
- – 2017~2022: Assistant Professor, UNIST
- – 2015~2017: Postdoctoral Researcher, Wyss Institute at Harvard University
- – 2015~2015: Postdoctoral Researcher, Seoul National University
학력
- – 2015: M.S.&Ph.D. Animal Biotechnology, Seoul National University, Korea.
- – 2011: B.S. Animal Biotechnology, Seoul National University, Korea
수상 / 명예 / 회원
- – Member of the International Brain Barriers Society (IBBS)
- – Member of the Korean BioChip Society
- – Member of the Korean Tissue Engineering and Regenerative Medicine Society
- – Member of the Korean Society for Biomaterials (KSBM)
- – 2019, Young Scientist Award (KSBM)